Publications 2025

1. Single-cell RNA-sequencing as a potential approach for studying intratumor heterogeneity in pleural mesothelioma.

   Alay A, Marín R, Aliagas E, Gausachs M, Ruiz-Gil M, Macia I, Ojanguren A, Padrones S, Dorca E, Brenes J, Palmero R, Moreno V, Heyn H, Cordero D, Nadal E, Solé X. Lung Cancer. 2025 Sep;207():108679. doi: 10.1016/j.lungcan.2025.108679. Epub: 2025 Aug 5. PMID: 40782703

2. Hemodynamic Assessment of Arterial Perfusion by Using the Ultrasonographic Hand Acceleration Time: Protocol for a Cross-Sectional Prospective Descriptive Study.

   Gonzalo B, Videla S, Moranas J, Carnaval T, Herranz C, Espinar E, Iborra E. JMIR Res Protoc. 2025 Aug 21;14():e64450. doi: 10.2196/64450. Epub: 2025 Aug 21. PMID: 40839871; PMCID: PMC12411789

3. NADPH oxidase 1/4 dual inhibition impairs transforming growth factor-beta protumorigenic effects in cholangiocarcinoma cancer-associated fibroblasts.

   Amengual J, Gonzalez-Sanchez E, Yáñez-Bartolome M, Sererols-Viñas L, Ravichandra A, Guiton C, Fuste NP, Alay A, Hijazo-Pechero S, Martín-Mur B, Gut M, Esteve-Codina A, Cantos-Cortes A, Espinosa-Sotelo R, Ramos E, Serrano T, Calvo M, Laquente B, Ferrer J, Pons G, Mendez-Lucas A, Dooley S, Ilyas SI, Vallette M, Aoudjehane L, Lequoy M, Fouassier L, Coulouarn C, Affò S, Scheiter A, Calvisi DF, Tian TV, Fabregat I, Vaquero J. Signal Transduct Target Ther. 2025 Aug 18;10(1):257. doi: 10.1038/s41392-025-02347-z. Epub: 2025 Aug 18. PMID: 40820091; PMCID: PMC12358586

4. From Rare to Common: Genetic Insights into TLR7 Variants in a Multicentric Spanish Study on COVID-19 Severity.

   Antolí A, Vargas-Parra G, Sierra-Fortuny A, Gomez-Vazquez JL, Rofes P, Munté E, Viana-Errasti J, Marín-Montes R, López-Doriga A, Feliubadaló L, Del Valle J, Pérez-González A, Poveda E, Solanich X, Lázaro C. J Clin Immunol. 2025 May 27;45(1):100. doi: 10.1007/s10875-025-01892-0. Epub: 2025 May 27. PMID: 40423910; PMCID: PMC12116960

5. Waist Circumference, a Body Shape Index, and Molecular Subtypes of Colorectal Cancer: A Pooled Analysis of Four Cohort Studies.

   Chalitsios CV, Markozannes G, Papagiannopoulos C, Aglago EK, Berndt SI, Buchanan DD, Campbell PT, Cao Y, Chan AT, Dimou N, Drew DA, French AJ, Georgeson P, Giannakis M, Gruber SB, Gunter MJ, Harrison TA, Hoffmeister M, Hsu L, Huang WY, Hullar MAJ, Huyghe JR, Lynch BM, Moreno V, Newton CC, Nowak JA, Obón-Santacana M, Ogino S, Qu C, Schmit SL, Steinfelder RS, Sun W, Thomas CE, Toland AE, Trinh QM, Ugai T, Um CY, Van Guelpen B, Zaidi SH, Murphy N, Peters U, Phipps AI, Tsilidis KK. Cancer Epidemiol Biomarkers Prev. 2025 Apr 3;34(4):568-577. doi: 10.1158/1055-9965.EPI-24-1534. PMID: 39898780; PMCID: PMC12132105

6. TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells.

   Priego N, de Pablos-Aragoneses A, Perea-García M, Pieri V, Hernández-Oliver C, Álvaro-Espinosa L, Rojas A, Sánchez O, Steindl A, Caleiras E, García F, García-Martín S, Graña-Castro O, García-Mulero S, Serrano D, Velasco-Beltrán P, Jiménez-Lasheras B, Egia-Mendikute L, Rupp L, Stammberger A, Meinhardt M, Chaachou-Charradi A, Martínez-Saez E, Bertero L, Cassoni P, Mangherini L, Pellerino A, Rudà R, Soffietti R, Al-Shahrour F, Saftig P, Sanz-Pamplona R, Schmitz M, Crocker SJ, Calvo A, Palazón A, RENACER, Valiente M. Cancer Discov. 2025 Jan 13;15(1):179-201. doi: 10.1158/2159-8290.CD-24-0134. PMID: 39354883; PMCID: PMC11726018

7. Characterization of Additive Gene-environment Interactions For Colorectal Cancer Risk.

   Thomas CE, Lin Y, Kim M, Kawaguchi ES, Qu C, Um CY, Lynch BM, Van Guelpen B, Tsilidis K, Carreras-Torres R, van Duijnhoven FJB, Sakoda LC, Campbell PT, Tian Y, Chang-Claude J, Bézieau S, Budiarto A, Palmer JR, Newcomb PA, Casey G, Le Marchandz L, Giannakis M, Li CI, Gsur A, Newton C, Obón-Santacana M, Moreno V, Vodicka P, Brenner H, Hoffmeister M, Pellatt AJ, Schoen RE, Dimou N, Murphy N, Gunter MJ, Castellví-Bel S, Figueiredo JC, Chan AT, Song M, Li L, Bishop DT, Gruber SB, Baurley JW, Bien SA, Conti DV, Huyghe JR, Kundaje A, Su YR, Wang J, Keku TO, Woods MO, Berndt SI, Chanock SJ, Tangen CM, Wolk A, Burnett-Hartman A, Wu AH, White E, Devall MA, Díez-Obrero V, Drew DA, Giovannucci E, Hidaka A, Kim AE, Lewinger JP, Morrison J, Ose J, Papadimitriou N, Pardamean B, Peoples AR, Ruiz-Narvaez EA, Shcherbina A, Stern MC, Chen X, Thomas DC, Platz EA, Gauderman WJ, Peters U, Hsu L. Epidemiology. 2025 Jan 1;36(1):126-138. doi: 10.1097/EDE.0000000000001795. Epub: 2024 Sep 24. PMID: 39316822; PMCID: PMC12142706

8. Body mass index at birth and early life and colorectal cancer: A two-sample Mendelian randomization analysis in European and East Asian genetic similarity populations.

   Papadimitriou N, Murphy N, Jenab M, Chen Z, Brenner H, Kweon SS, Le Marchand L, Moreno V, Platz EA, van Duijnhoven FJB, Cheng I, Pai RK, Phipps AI, Peters U, Zheng W, Hughes DJ. Pediatr Obes. 2025 Jan;20(1):e13186. doi: 10.1111/ijpo.13186. Epub: 2024 Nov 25. PMID: 39587448; PMCID: PMC11669838